Fig. 1

Micrographs of cells. Unattached cells were present on the fifth day. Adherent cells showed spindle or long triangle shape (a). There were almost no unattached cells in the third passage (b). The control cells were randomly arranged without any direction (c), whereas the experimental cells rearranged in a specific direction similar to a school of fish (d–f). Scale bars: 100 μm. The area of cell spreading decreased gradually (g). The ratio of the lateral axis/vertical axis increased slightly (h). ^*P < 0.05