Table 9 Area under the receiving operator curve (mean and 95% confidence interval) of the traditional FOT parameters in the identification of the bronchodilator response in patients with work-related asthma
AUC | Se (%) | Sp (%) | Cut-off | |
|---|---|---|---|---|
R0 | 0.699 0.570–0.829 | 74.1 55.4–88.1 | 58.0 39.1–75.5 | > 2.72 |
Rm | 0.694 0.563–0.825 | 83.8 66.3–94.5 | 51.6 33.1–69.8 | > 2.39 |
R4 | 0.708 0.580–0.835 | 93.5 78.6–99.2 | 38.7 21.8–57.8 | > 2.00 |
R12 | 0.690 0.558–0.822 | 64.5 45.4–80.8 | 70.9 52.0–85.8 | > 2.46 |
R20 | 0.691 0.558–0.824 | 74.1 55.4–88.1 | 61.2 42.2–78.2 | > 2.20 |
S | 0.686 0.554–0.817 | 77.4 58.9–90.4 | 51.61 33.1–69.8 | ≤ − 19.9 |
R4 − R20 | 0.677 0.542–0.813 | 61.2 42.2–78.2 | 70.9 52.0–85.8 | > 0.30 |
Xm | 0.629 0.489–0.768 | 45.1 27.3–64.0 | 87.1 70.2–96.4 | ≤ − 0.35 |
Fr | 0.634 0.494–0.773 | 51.6 33.1–69.8 | 77.4 58.9–90.4 | > 19.5 |
Cdyn | 0.706 0.574–0.837 | 58.0 39.1–75.5 | 87.1 70.2–96.4 | ≤ 14.3 |
Axt | 0.697 0.566–0.828 | 51.6 33.1–69.8 | 83.8 66.3–94.5 | > 18.6 |
Axi | 0.665 0.530–0.800 | 61.29 42.2 – 78.2 | 64.52 45.4 – 80.8 | ≤ 9.10 |
Z4 | 0.726 0.601–0.851 | 74.1 55.4–88.1 | 61.2 42.2–78.2 | > 3.36 |