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Table 2 Spirometric and plethysmographic characteristics of control individuals and patients with work-related asthma

From: Combined forced oscillation and fractional-order modeling in patients with work-related asthma: a case–control study analyzing respiratory biomechanics and diagnostic accuracy

 

Control (n = 31)

Work-related asthma before BD (n = 31)

Work-related asthma post BD (n = 31)

Spirometry

 FEV1 (L)

2.8 ± 0.7

2.3 ± 0.6**

2.5 ± 0.7‡‡

 FEV1 (%)

93.1 ± 15.0

75.6 ± 19.2***

81.3 ± 17.4‡‡‡‡

 FVC (L)

3.5 ± 0.8

3.1 ± 0.7

3.3 ± 0.8

 FVC (%)

95.3 ± 15.1

84.1 ± 15.0**

86.6 ± 14.0‡‡

 FEV1/FVC

79.9 ± 6.7

72.6 ± 11.7*

76.4 ± 10.2

 FEF 25–75%

2.9 ± 1.1

2.0 ± 1.1**

2.4 ± 1.2

 FEF/CVF

0.7 ± 0.2

0.6 ± 0.3

0.7 ± 0.3

 EPF

7.1 ± 1.8

5.5 ± 2.0**

5.7 ± 2.2

Plethysmography

 VC (L)

3.73 ± 0.6

2.95 ± 0.7***

3.16 ± 0.6

 IC (L)

2.45 ± 0.6

2.69 ± 0.6*

2.93 ± 0.6

 ERV (L)

1.31 ± 0.08

0.33 ± 0.2***

0.26 ± 0.2

 TLC (L)

5.48 ± 0.9

5.27 ± 1.1

5.14 ± 1.3

 TV (L)

0.86 ± 0.3

0.87 ± 0.2

 RV (L)

1.7 ± 0.3

2.3 ± 0.8***

2.0 ± 0.9

 RV/TLC

31.11 ± 3.1

43.8 ± 12.9***

39 ± 11.6

 FRC

3.02 ± 0.35

2.86 ± 1.2

2.3 ± 1.0

 TGV

3.2 ± 1.3

2.7 ± 1.26

 Raw

1.38 ± 0.09

5.8 ± 5.2***

3.7 ± 3.1‡‡

 SGaw

0.24 ± 0.02

0.12 ± 0.09***

0.16 ± 0.1

  1. Data are mean ± SD; % = percentage of the predicted values
  2. FEV1: forced expiratory volume in the first second, FVC: forced vital capacity, FEF: forced expiratory flow between 25 and 75% of the FVC, %: percentage of the predicted values, EPF: expiratory peak flow, TLC: total lung capacity, FRC: functional residual capacity, ERV: expiratory reserve volume, RV: residual volume, Raw: airway resistance, TGV: thoracic gas volume, SGaw: specific airway resistance
  3. *p < 0.05 related to control group
  4. **p < 0.01 related to control group
  5. ***p < 0.001 related to control group
  6. p < 0.05 related to pre-BD
  7. ‡‡p < 0.01 related to pre-BD