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Table 2 Evaluation of two sample t tests between 37 NC and 20 AD subjects

From: Construction and comparative evaluation of different activity detection methods in brain FDG-PET

MNI

Cluster size (voxels)

Max. t-score

Voxel (x, y, z)

Brain area

CAD4D

24,350

13.04

(−40; −72; 42)

Left precuneus, parietal lobe

SPM

23,518

11.88

(−36; −74; 40)

Left precuneus, parietal lobe

TAL

Cluster size (voxels)

Max. t-score

Voxel (x, y, z)

Brain area

CAD4D(TAL)

13,552

11.93

(−38; −65; 27)

Left middle temporal gyrus, temporal lobe

SPM(TAL)

12,980

11.44

(−37; −73; 35)

Left precuneus, parietal lobe

NEUROSTAT

14,637

12.85

(−40; −71; 33)

Angular gyrus, temporal lobe

  1. Extracted total hypometabolic cluster size at p < 0.001 (as displayed in Fig. 5), maximum t-score with position and corresponding brain area
  2. Upper table: using CAD4D and SPM normalized images in MNI space
  3. Lower table: using CAD4D, SPM and NEUROSTAT normalized images in Talairach space