Table 2 Spirometric, plethysmografic and diffusion characteristics of the studied subjects
From: Forced oscillations and respiratory system modeling in adults with cystic fibrosis
|  | Control group (n = 23) | Cystic fibrosis (n = 27) | p |
|---|---|---|---|
Spirometry | Â | Â | Â |
FVC (L) | 4.2 ± 1.0 | 3.5 ± 1.3 | 0.03 |
FVC (%) | 101.7 ± 13.0 | 84.1 ± 2 5.4 | 0.004 |
FEV1 (L) | 3.7 ± 0.8 | 2.3 ± 1.1 | 0.0001 |
FEV1 (%) | 105.2 ± 13.8 | 65.8 ± 28.6 | 0.0001 |
FEV1/FVC | 88.7 ± 4.4 | 64.4 ± 13.9 | 0.0001 |
FEF25–75% (L) | 4.6 ± 1.3 | 1.6 ± 1.3 | 0.0001 |
FEF25–75% (%) | 113.3 ± 26.7 | 39.1 ± 30.0 | 0.0001 |
FEF25–75%/FVC | 110.7 ± 23.8 | 41.8 ± 26.6 | 0.0001 |
Plethysmography | Â | Â | Â |
TLC (L) | 5.6 ± 1.0 | 5.7 ± 1.4 | ns |
TLC (%) | 99.4 ± 12.2 | 100.2 ± 19.2 | ns |
FRC (L) | 2.7 ± 0.6 | 3.4 ± 1.3 | ns |
FRC (%) | 88.3 ± 17.4 | 100.6 ± 31.2 | ns |
RV (L) | 1.6 ± 0.5 | 2.3 ± 1.4 | 0.008 |
RV (%) | 101.5 ± 33.0 | 149.0 ± 95.2 | 0.007 |
RV/TLC | 27.8 ± 8.7 | 39.2 ± 15.9 | 0.004 |
RV/TLC (%) | 100.8 ± 28.6 | 144.4 ± 59.9 | 0.001 |
FRC/TLC | 49.9 ± 8.0 | 56.3 ± 11.1 | ns |
Raw (cmH2O/L/s) | 0.73 ± 0.28 | 1.94 ± 1.31 | 0.0001 |
SGaw (cmH2O−1 s−1) | 0.49 ± 0.24 | 0.19 ± 0.12 | 0.0001 |