A computational model of skeletal muscle metabolism linking cellular adaptations induced by altered loading states to metabolic responses during exercise

Table 3 Muscle tissue cells species concentrations at rest for the three different loading states (concentrations are in the units of mM).

Species	Sedentary	Loaded	Unloaded
GLU	0.525	0.525	0.525
GLY	95.0	110.0	110.0
G6P	0.253	0.253	0.253
GA3P	0.08	0.08	0.08
BPG	0.08	0.08	0.08
PYR	0.0475	0.0475	0.0475
LAC	1.75	1.75	1.75
ALA	1.3	1.3	1.3
TGL	14.8	17.4	18.5
GLC	0.062	0.062	0.062
FFA	0.57	0.57	0.57
FAC	0.00348	0.00348	0.00348
ACoA	0.00223	0.00223	0.00223
CIT	0.103	0.103	0.103
AKG	0.0125	0.0125	0.0125
SCoA	0.123	0.123	0.123
SUC	0.095	0.095	0.095
MAL	0.0975	0.0975	0.0975
OXA	0.003	0.003	0.003
CO2	23.6	23.6	23.6
O2	3.0	3.0	3.0
PCr	20.0	20.0	20.0
Cr	10.0	10.0	10.0
Pi	2.7	2.7	2.7
CoA	0.0255	0.0255	0.0255
NADH	0.05	0.05	0.05
NAD+	0.45	0.45	0.45
ATP	6.3	6.3	6.3
ADP (free)	0.02	0.02	0.02
AMP (free)	6.0E-5	6.0E-5	6.0E-5

The species concentrations are obtained from a variety literature sources on skeletal muscle metabolism (for references, see the text in Method section)

ISSN: 1475-925X