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Table 4 Comparison of pupillometric parameters between the two follow-up time-points in subject 1 (Both Tests)

From: Pupillometric analysis for assessment of gene therapy in Leber Congenital Amaurosis patients

Par.

Test 1

Test 2

 

1 year time-point

3 year time-point

 

1 year time-point

3 year time-point

 
 

Med

25 th

75 th

Med

25 th

75 th

P

Med

25 th

75 th

Med

25 th

75 th

P

BD

4.56

4.20

4.77

4.14

3.71

4.59

<0.01

4.56

4.00

4.81

4.03

3.93

4.24

<0.01

MA

4.37

3.91

4.60

4.06

3.52

4.38

<0.01

4.22

3.67

4.73

3.95

3.70

4.06

<0.01

RA

0.16

0.01

0.39

0.06

0.01

0.25

0.06

0.16

0.06

0.29

0.16

0.05

0.28

0.26

PC

0.96

0.92

1.00

0.99

0.94

1.00

0.11

0.97

0.93

0.99

0.96

0.93

0.99

0.42

-RT

0.74

0.28

1.00

0.80

0.24

1.04

0.77

0.94

0.68

1.22

1.00

0.48

1.24

0.77

CV

0.26

0.02

0.42

0.13

0.04

0.30

0.30

0.14

0.07

0.33

0.18

0.05

0.31

0.48

  1. Par: parameters.
  2. Med: median.
  3. 25th : 25 th percentile (first quartile)/75th : 75 th percentile (third quartile).
  4. P: p-value.